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10 items by relevance
1 Conference paper

Bioprocess for testing engineered cho cell lines using single-use bioreactors

Decker, Marianne

Quality verification of engineered cell lines with improved technological qualities suited for industrial production of therapeutic proteins. Parameters in focus for optimization are homogenous glycosylation, fast growth, limited apoptosis, high yield and facilitated downstream processing.

Year: 2015

Language: English

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2 Conference paper

Bioprocess facility for test of Engineered CHO cell lines in Single-use bioreactors

Decker, Marianne; Lund Jensen, Kristian; Javidi, Elham Maria; Voldborg, Bjørn Gunnar

into an industrial relevant context by high throughput generation and screening of genetically manipulated CHO cell lines through an iterative loop. To evaluate whether or not the genetic manipulations improved cell performance, the cell are rigorously tested within the Bioprocess facility.

Year: 2017

Language: English

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