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10 items by relevance
1 Journal article

Probabilistic cumulative risk assessment of anti-androgenic pesticides in food

Müller, Anne Kirstine; Bosgra, Sieto; Boon, Polly E.; van der Voet, Hilko; Nielsen, Elsa; Ladefoged, Ole

Food and Chemical Toxicology — 2009, Volume 47, Issue 12, pp. 2951-2962

In this paper, we present a cumulative risk assessment of three anti-androgenic pesticides (vinclozolin, procymidone and prochloraz) using the relative potency factor (RPF) approach and an integrated probabilistic risk assessment (IPRA) model. RPFs for each substance were estimated for three reproductive endpoints (ano-genital distance, and weights of the seminal vesicles and the musculus levator ani/bulbocavernosus) in male rat foetuses exposed in utero. The cumulative dietary intake was estimated based on consumption data and residue data from the Netherlands. The IPRA model combines vari...

Year: 2009

Language: English

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igk fobep nh cjaldm
2 Conference paper

Probabilistic cumulative risk assessment of anti-androgenic pesticides in food

Müller, Anne Kirstine; Bosgra, S.; Boon, P. E.; Voet, H. van der; Nielsen, Elsa; Ladefoged, Ole

Year: 2008

Language: English

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bnokpadehgl ic fmj
3 Journal article · Conference paper

Probabilistic cumulative risk assessment of anti-androgenic pesticides in food

Müller, Anne Kirstine; Nielsen, Elsa

Toxicology Letters — 2008, Volume 180, Issue S, pp. S72

A cumulative risk assessment of three anti-androgenic pesticides vinclozolin, procymidone and prochloraz in combination has been carried out using an Integrated Probabilistic Risk Assessment (IPRA) model. In the model, variability in both exposure and sensitivity between individuals were combined

Year: 2008

Language: English

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oj lgd imnpfkcheab

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