Other
Discovery and Assesment of New Target Sites for Anti-HIV Therapies
University of Oxford1
York University Toronto2
New Jersey Institute of Technology3
Dynamical systems, Department of Mathematics, Technical University of Denmark4
Department of Mathematics, Technical University of Denmark5
CSIRO6
Wilfrid Laurier University7
Victoria University of Wellington8
Gustavus Adolphus College9
The HIV viruses infect cells by endocytosis and takes over parts of the cells reaction pathways in order to reproduce itself and spread the infection. One such pathway is the mammalian inflammatory signaling, which invoke NF-κB as the principal transcription factor. A treatment against HIV could be based on blocking the NF-κB pathway by a suitably designed drug.
The aim of the current project is to investigate the feasibility of this idea by using mathematical modelling of the NF-κB pathway.
| Language: | English |
|---|---|
| Year: | 2008 |
| Proceedings: | Fields-MITACS Industrial Problem-Solving Workshop |
| Types: | Other |
| ORCIDs: | 0000-0003-0820-8722 |
