Journal article
Genomics of an emerging clone of Salmonella serovar Typhimurium ST313 from Nigeria and the Democratic Republic of Congo
Comparative Microbial Genomics, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark1
National Food Institute, Technical University of Denmark2
Division of Epidemiology and Microbial Genomics, National Food Institute, Technical University of Denmark3
Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark4
Immunological Bioinformatics, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark5
Translational Genomics Research Institute6
Division of Microbiology and Risk Assessment, National Food Institute, Technical University of Denmark7
University of Ibadan8
Saint-Pierre University Hospital9
We showed in a limited number of isolates that S. Typhimurium ST313 is a prevalent sequence-type causing gastrointestinal diseases and septicemia in patients from Nigeria and DRC. We found three distinct phylogenetic clusters based on the origin of isolation suggesting some spatial evolution. Comparative genomics showed an interesting putative virulence fragment (ST313-TD) unique to S.
Typhimurium ST313 and invasive S. Dublin.
Language: | English |
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Year: | 2013 |
Pages: | 696-706 |
ISSN: | 19722680 and 20366590 |
Types: | Journal article |
DOI: | 10.3855/jidc.3328 |
ORCIDs: | Leekitcharoenphon, Pimlapas , Svendsen, Christina Aaby , Aarestrup, Frank Møller and Hendriksen, Rene S. |
Africa Child Child, Preschool Cluster Analysis DNA, Bacterial Democratic Republic of the Congo Electrophoresis, Gel, Pulsed-Field Female Genome, Bacterial Genomics Genotype Humans Infant Male Microbial Sensitivity Tests Molecular Sequence Data Multilocus Sequence Typing Nigeria Phylogeny Salmonella Infections Salmonella typhimurium Virulence Factors