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Journal article

Challenges in modeling the human gut microbiome

From

Chalmers University of Technology1

King's College London2

Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark3

Yeast Cell Factories, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark4

A paper by Magnúsdóttir et al.1 in a previous issue describes the generation of genome-scale metabolic models (GEMs) for 773 members of the human gut microbiota, referred to as AGORA. It represents a valuable contribution to quantitative analyses of how the many different species of gut microbiota interact and influence host metabolism.

At the same time, a detailed analysis of the models described in this work raises several questions.

Language: English
Publisher: Nature Publishing Group US
Year: 2018
Pages: 682-686
Journal subtitle: Science and Business of Biotechnology
ISSN: 15461696 and 10870156
Types: Journal article
DOI: 10.1038/nbt.4213
ORCIDs: 0000-0001-5834-4533 and 0000-0002-9955-6003

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