Journal article
Model visualization for evaluation of biocatalytic processes
Biocatalysis offers great potential as an additional, and in some cases as an alternative, synthetic tool for organic chemists, especially as a route to introduce chirality. However, the implementation of scalable biocatalytic processes nearly always requires the introduction of process and/or biocatalyst enhancements to ensure effective scale-up.
This paper describes a paradigm for the purpose of evaluating biocatalytic processes in order to provide guidance on process and biocatalyst modification. The paradigm is illustrated with the biocatalytic synthesis of S,S-ethylenediaminedisuccinic acid (S,S-EDDS), a biodegradable chelant, and is characterised by the use of model visualization using `windows of operation".
Language: | English |
---|---|
Year: | 2008 |
Pages: | 96-103 |
ISSN: | 17443571 and 09603085 |
Types: | Journal article |
DOI: | 10.1016/j.fbp.2008.03.006 |
ORCIDs: | Woodley, John |