Journal article
A support structure for biomimetic applications
Department of Micro- and Nanotechnology, Technical University of Denmark1
Aquaporin A/S2
Bioanalytics Group, Biomedical Micro Systems Section, Department of Micro- and Nanotechnology, Technical University of Denmark3
Biomedical Micro Systems Section, Department of Micro- and Nanotechnology, Technical University of Denmark4
Biophysics and Fluids, Department of Physics, Technical University of Denmark5
Department of Physics, Technical University of Denmark6
Polymeric Enabling Microsystems Group, Polymer Micro and Nano Engineering Section, Department of Micro- and Nanotechnology, Technical University of Denmark7
Polymer Micro and Nano Engineering Section, Department of Micro- and Nanotechnology, Technical University of Denmark8
Water filtration on the basis of aquaporin molecules incorporated in an artificial lipid bilayer requires a microporous support membrane. We describe a new microfabrication method based on CO2-laser ablation to generate support membranes with homogeneous apertures ranging from 300 mu m down to 84 mu m in diameter.
They are arranged in arrays with the densest packaging having a perforation level of up to 60%. The apertures are surrounded by a smooth bulge that is formed by melted material ejected from the aperture during laser ablation. Polydimethylsiloxane (PDMS) replicas were used to visualize and analyse these bulges.
The overall area covered so far has been 4 cm(2) but upscaling to larger footprints, e. g. square metres, is currently being investigated.
| Language: | English |
|---|---|
| Year: | 2009 |
| Pages: | 025026 |
| ISSN: | 13616439 and 09601317 |
| Types: | Journal article |
| DOI: | 10.1088/0960-1317/19/2/025026 |
| ORCIDs: | Helix Nielsen, Claus |
