Journal article
Enhanced 13C NMR detects extended reaction networks in living cells
Hyperpolarization & Metabolism, Magnetic Resonance, Department of Health Technology, Technical University of Denmark1
Magnetic Resonance, Department of Health Technology, Technical University of Denmark2
Department of Health Technology, Technical University of Denmark3
Department of Chemistry, Technical University of Denmark4
Technical University of Denmark5
Insights into intracellular chemistry have remained sparse, but would be impactful for the advancement of biomedicine and bioproduction. A suitable 13C NMR approach provides improvements in sensitivity that make extended reaction networks and assay time windows, previously inaccessible cell densities and relative flux measurements accessible in living cells.
Language: | English |
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Publisher: | The Royal Society of Chemistry |
Year: | 2021 |
Pages: | 10572-10575 |
ISSN: | 1364548x and 13597345 |
Types: | Journal article |
DOI: | 10.1039/d1cc03838a |
ORCIDs: | Jensen, Pernille Rose , Sannelli, Francesca and Meier, Sebastian |