Journal article
InterMap3D: predicting and visualizing co-evolving protein residues
InterMap3D predicts co-evolving protein residues and plots them on the 3D protein structure. Starting with a single protein sequence, InterMap3D automatically finds a set of homologous sequences, generates an alignment and fetches the most similar 3D structure from the Protein Data Bank (PDB). It can also accept a user-generated alignment.
Based on the alignment, co-evolving residues are then predicted using three different methods: Row and Column Weighing of Mutual Information, Mutual Information/Entropy and Dependency. Finally, InterMap3D generates high-quality images of the protein with the predicted co-evolving residues highlighted.
Language: | English |
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Publisher: | Oxford University Press |
Year: | 2009 |
Pages: | 1963-1965 |
ISSN: | 13674811 , 13674803 , 14602059 and 02667061 |
Types: | Journal article |
DOI: | 10.1093/bioinformatics/btp335 |
ORCIDs: | Wernersson, Rasmus and Pedersen, Anders Gorm |