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Journal article · Book chapter

Probe design for expression arrays using OligoWiz

Edited by Dufva, Martin

From

Department of Systems Biology, Technical University of Denmark1

Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark2

Since all measurements from a DNA microarray is dependant on the probes used, a good choice of probes is of vital importa nce when designing custom micro-arrays. This chapter describes how to de sign expression arrays using the “ OligoWiz ” software suite. The general desired features of good probes and the issues which probe design must address are introduced and a conceptual (rather than mathematical) description of how OligoWiz scores the quality of th e potential probes is presented.

This is followed by a detailed step-by-step guide to designing expression arrays with OligoWiz.

Language: English
Publisher: Humana Press
Year: 2014
Pages: 23-36
Series: Methods in Molecular Biology
Journal subtitle: Methods and Protocols
ISBN: 1597455385 , 193411569X , 193411569x , 9781597455381 and 9781934115695
ISSN: 10643745
Types: Journal article and Book chapter
DOI: 10.1007/978-1-59745-538-1_2
ORCIDs: Wernersson, Rasmus

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