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Journal article

Effect of tulathromycin on the carrier status of Actinobacillus pleuropneumoniae serotype 2 in the tonsils of pigs

From

Bacteriology & Pathology, Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark1

Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark2

National Veterinary Institute, Technical University of Denmark3

Section for Veterinary Epidemiology and public sector consultancy, Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark4

The effect of a single or double dose of tulathromycin was evaluated in pigs carrying Actinobacillus pleuropneumoniae serotype 2 in their tonsils. Twenty-nine pigs from a reinfected specific pathogen-free-herd were selected from animals testing positive in an A pleuropneumoniae serotype 2-specific PCR test on tonsil scrapings and they were divided into three groups.

The pigs in group I were treated subcutaneously with 2.5 mg/kg tulathromycin on day 0, the pigs in group 2 were treated with 2.5 mg/kg tulathromycin on days 0 and 4, and the pigs in group 3 were left untreated as controls. The pigs were tested by PCR on tonsil scrapings on days 0, 4, 11 and 33, and on day 33 all the animals were euthanased.

There were no significant differences between the numbers of PCR-positive animals in the three groups on any of the sampling dates.

Language: English
Year: 2008
Pages: 445-447
ISSN: 02143909 , 00424900 and 20427670
Types: Journal article
DOI: 10.1136/vr.163.15.445
ORCIDs: Stockmarr, Anders

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