Journal article
Family-based cognitive behavioural therapy versus family-based relaxation therapy for obsessive-compulsive disorder in children and adolescents: protocol for a randomised clinical trial (the TECTO trial)
University of Copenhagen1
Department of Applied Mathematics and Computer Science, Technical University of Denmark2
Statistics and Data Analysis, Department of Applied Mathematics and Computer Science, Technical University of Denmark3
Copenhagen University Hospital Herlev and Gentofte4
Aarhus University5
Department of Micro- and Nanotechnology, Technical University of Denmark6
Background: Cognitive behavioural therapy (CBT) is the recommended first-line treatment for children and adolescents with obsessive-compulsive disorder (OCD), but evidence concerning treatment-specific benefits and harms compared with other interventions is limited. Furthermore, high risk-of-bias in most trials prevent firm conclusions regarding the efficacy of CBT.
We investigate the benefits and harms of family-based CBT (FCBT) versus family-based psychoeducation and relaxation training (FPRT) in youth with OCD in a trial designed to reduce risk-of-bias. Methods: This is an investigator-initiated, independently funded, single-centre, parallel group superiority randomised clinical trial (RCT).
Outcome assessors, data managers, statisticians, and conclusion drawers are blinded. From child and adolescent mental health services we include patients aged 8-17years with a primary OCD diagnosis and an entry score of >= 16 on the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS). We exclude patients with comorbid illness contraindicating trial participation; intelligence quotient
| Language: | English |
|---|---|
| Publisher: | BioMed Central |
| Year: | 2022 |
| Pages: | 204 |
| ISSN: | 1471244x |
| Types: | Journal article |
| DOI: | 10.1186/s12888-021-03669-2 |
| ORCIDs: | 0000-0003-3647-4585 , Clemmensen, Line Katrine Harder , Olsen, Markus Harboe , 0000-0002-1622-3108 and 0000-0003-0818-8338 |
Adolescent Adolescents Child Children Cognitive Behavioral Therapy Cognitive Behavioral Therapy/methods Cognitive behavioural therapy Family Therapy Humans Obsessive-Compulsive Disorder Obsessive-Compulsive Disorder/psychology Obsessive-compulsive disorder Outcome Assessment, Health Care Psychiatry Psycho-education and relaxation training RC435-571 Randomised clinical trial Randomized Controlled Trials as Topic Relaxation Therapy Treatment Outcome Treatment effects Youth
