Book chapter
Dynamic Modeling and Control of a Continuous Biopharmaceutical Manufacturing Plant
Tarbiat Modarres University1
Technical University of Denmark2
PILOT PLANT, Department of Chemical and Biochemical Engineering, Technical University of Denmark3
Department of Chemical and Biochemical Engineering, Technical University of Denmark4
PROSYS - Process and Systems Engineering Centre, Department of Chemical and Biochemical Engineering, Technical University of Denmark5
Amirkabir University of Technology6
KT Consortium, Department of Chemical and Biochemical Engineering, Technical University of Denmark7
The application of model-based tools in biopharmaceutical industry is an active area of research to design, control and analysis of existing and future production of new drugs and therapeutics. In this chapter, a reference plant-wide model for production of a biopharmaceutical compound is proposed. It captures the generic process dynamics of a biopharmaceutical process.
As such, it is well-suited to use as a test problem to evaluate different processing scenarios in continuous and semi-continuous fermentation processes.
| Language: | English |
|---|---|
| Publisher: | Springer |
| Year: | 2022 |
| Pages: | 323-353 |
| Series: | Springer Optimization and Its Applications |
| ISBN: | 3030909239 , 3030909247 , 9783030909239 and 9783030909246 |
| ISSN: | 19316836 and 19316828 |
| Types: | Book chapter |
| DOI: | 10.1007/978-3-030-90924-6_12 |
| ORCIDs: | Jones, Mark Nicholas , Udugama, Isuru , Gernaey, Krist V. and Mansouri, Seyed Soheil |
