Stochastic simulation-based superstructure optimization framework for process synthesis and design under uncertainty

Advances in simulation and optimization technologies coupled with the continued growth in computing power now increasingly pave the way for the development of advanced model-based engineering design frameworks. In this work, we propose an extensive computational framework, which brings together state-of-the-art engineering practices, such as high fidelity process simulation, superstructure-based conceptual design, global sensitivity analysis, Monte Carlo procedures for uncertainty quantification, and a stochastic simulation-based design space optimizer in order to foster decision making under uncertainty.

The capabilities of the framework are highlighted in a case study, which addresses the challenges of how to synthesize and design wastewater treatment plant configurations under influent uncertainties. In order to handle multiple stochastic constraints, a black-box solver using a new infill criterion for surrogate-based optimization is also proposed.

The results demonstrate the promising potential of the simulation and sampling-based framework for effectively addressing stochastic design problems arising in broader engineering domains.