Journal article
Microwave-gated dynamic nuclear polarization
Swiss Federal Institute of Technology Lausanne1
Sorbonne Université2
Department of Automation, Technical University of Denmark3
Center for Hyperpolarization in Magnetic Resonance, Centers, Technical University of Denmark4
Department of Electrical Engineering, Technical University of Denmark5
Center for Magnetic Resonance, Department of Electrical Engineering, Technical University of Denmark6
Dissolution dynamic nuclear polarization (D-DNP) has become a method of choice to enhance signals in nuclear magnetic resonance (NMR). Recently, we have proposed to combine cross-polarization (CP) with D-DNP to provide high polarization P((13)C) in short build-up times. In this paper, we show that switching microwave irradiation off for a few hundreds of milliseconds prior to CP can significantly boost the efficiency.
By implementing microwave gating, (13)C polarizations on sodium [1-(13)C]acetate as high as 64% could be achieved with a polarization build-up time constant as short as 160 s. A polarization of P((13)C) = 78% could even be reached for [(13)C]urea.
| Language: | English |
|---|---|
| Publisher: | The Royal Society of Chemistry |
| Year: | 2016 |
| Pages: | 30530-30535 |
| ISSN: | 14639084 and 14639076 |
| Types: | Journal article |
| DOI: | 10.1039/c6cp05587g |
| ORCIDs: | Ardenkjær-Larsen, Jan Henrik |
