Journal article
Simultaneous alignment and clustering of peptide data using a Gibbs sampling approach
Center for Biological Sequence Analysis, Technical University of Denmark, DK-2800 Lyngby, Denmark and1
Motivation: Proteins recognizing short peptide fragments play a central role in cellular signaling. As a result of high-throughput technologies, peptide-binding protein specificities can be studied using large peptide libraries at dramatically lower cost and time. Interpretation of such large peptide datasets, however, is a complex task, especially when the data contain multiple receptor binding motifs, and/or the motifs are found at different locations within distinct peptides.
Language: | Undetermined |
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Publisher: | Oxford University Press |
Year: | 2012 |
Pages: | 8-14 |
ISSN: | 13674811 , 14602059 and 13674803 |
Types: | Journal article |
DOI: | 10.1093/bioinformatics/bts621 |