Journal article
Aminocyclopentanols as sugar mimics. Synthesis from unsaturated bicyclic lactones by Overman rearrangement
Bicyclic cyclopentane lactones, prepared from bromodeoxyaldonolactones, were transformed into aminocyclopentanols with an Overman rearrangement as the key step. Two of the compounds prepared, 7 and 19, were found to be good inhibitors of jack bean alpha-mannosidase and beta-D-N-acetylglucosaminidase, respectively.
Language: | English |
---|---|
Publisher: | The Royal Society of Chemistry |
Year: | 2007 |
Pages: | 3164-3171 |
ISSN: | 14770539 and 14770520 |
Types: | Journal article |
DOI: | 10.1039/b710232a |