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Journal article

Traces of ATCV-1 associated with laboratory component contamination

By Kjartansdóttir, Kristín Rós1; Friis-Nielsen, Jens2,3,4; Asplund, Maria1; Mollerup, Sarah1; Mourier, Tobias1; Holm Jensen, Randi1; Arn Hansen, Thomas1; Rey-Iglesia, Alba1; Raith Richter, Stine1; Alquezar-Planas, David E.1; Olsen, Pernille V. S.1; Vinner, Lasse1; Fridholm, Helena1; Sicheritz-Pontén, Thomas2,3,5; Nielsen, Lars Peter6; Brunak, Søren2,3,4; Willerslev, Eske1; Gonzalez-Izarzugaza, Jose Maria2,3,4; Hansen, Anders Johannes1 ...and 9 more

From

University of Copenhagen1

Department of Systems Biology, Technical University of Denmark2

Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark3

Integrative Systems Biology, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark4

Metagenomics, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark5

Statens Serum Institut6

Yolken et al. (1) claim detection of Acanthocystis turfacea chlorella virus 1 (ATCV-1, gi119953744) in the normal human oropharyngeal viral flora and associate it with altered cognitive function. However, the reported presence of a freshwater algae virus, previously not known to infect other species, was based on a few sequence reads homologous to ATCV-1 identified with BLASTn.

These reads span relatively few bases (97–698 bp) per sample, dispersed over a minor fraction (0.03–0.24%) of the 288 kb ATCV-1 genome.

Language: English
Publisher: National Academy of Sciences
Year: 2015
Pages: E925-6
ISSN: 10916490 and 00278424
Types: Journal article
DOI: 10.1073/pnas.1423756112
ORCIDs: 0000-0002-5042-574X , 0000-0001-6615-1141 , Gonzalez-Izarzugaza, Jose Maria , 0000-0003-2727-1903 , 0000-0002-3768-9185 , 0000-0002-3081-3702 , 0000-0002-7081-6748 and 0000-0002-1890-2702
Keywords

Animals Behavior, Animal Biological Sciences Chlorella Cognition Female Humans Larynx Letters Male Memory Microbiology Moths Phycodnaviridae

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