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Journal article

Podospermic acid, 1,3,5-tri-O-(7,8-dihydrocaffeoyl) quinic acid from Podospermum laciniatum (Asteraceae)

By Zidorn, Christian1; Petersen, Bent O.2; Udovicic ́, Vedrana1; Larsen, Thomas Ostenfeld3,4; Duus, Jens Øllgaard2; Rollinger, Judith M.1; Ongania, Karl-Hans1; Ellmerer, Ernst P.1; Stuppner, Hermann1

From

University of Innsbruck1

Carlsberg Research Center2

Department of Systems Biology, Technical University of Denmark3

Natural Product Chemistry, Department of Systems Biology, Technical University of Denmark4

A phytochemical investigation of Podospermum laciniatum (L.) DC. (Asteraceae) yielded the new quinic acid derivative podospermic acid (1,3,5-tridihydrocaffeoylquinic acid), which was named after the genus it was isolated from. The structure was established by HR mass spectrometry and extensive 1D and 2D NMR spectroscopy.

Podospermic acid is the first naturally occurring dihydrocaffeoylquinic acid derivative. The chemosystematic impact and the radical scavenging activity of the new compound are discussed briefly. (C) 2004 Elsevier Ltd. All rights reserved.

Language: English
Year: 2005
Pages: 1291-1294
ISSN: 18733581 and 00404039
Types: Journal article
DOI: 10.1016/j.tetlet.2004.12.118
ORCIDs: Larsen, Thomas Ostenfeld
Keywords

Asteraceae CHEMISTRY, Cichorieae DERIVATIVES Natural products Phenolics Podospermum Science/technology Scorzonera laciniata Subtribe Scorzonerinae Tribe Lactuceae analytic method article asteraceae dihydrocaffeoylquinic acid mass spectrometry natural products nuclear magnetic resonance spectroscopy phenolics phytochemistry quinic acid subtribe scorzonerinae tribe lactuceae unclassified drug

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