Journal article
Efficient and highly enantioselective formation of the all-carbon quaternary stereocentre of lyngbyatoxin A
Indole 25, an advanced intermediate in a projected enantioselective total synthesis of lyngbyatoxin A 1, was prepared from allylic alcohol 11 in 9 steps and >95% ee, key transformations being the enantiospecific rearrangement of vinyl epoxide 14 and the Hemetsberger-Knittel reaction of azide 24.
Language: | English |
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Publisher: | The Royal Society of Chemistry |
Year: | 2006 |
Pages: | 4292-4298 |
ISSN: | 14770539 and 14770520 |
Types: | Journal article |
DOI: | 10.1039/b612578f |
ORCIDs: | Tanner, David |