Journal article
Three-dimensional MRI-linac intra-fraction guidance using multiple orthogonal cine-MRI planes
Department of Applied Mathematics and Computer Science, Technical University of Denmark1
Visual Computing, Department of Applied Mathematics and Computer Science, Technical University of Denmark2
University Medical Centre Utrecht3
University of Copenhagen4
Copenhagen University Hospital Herlev and Gentofte5
University of Sydney6
The introduction of integrated MRI-radiation therapy systems will offer live intra-fraction imaging. We propose a feasible low-latency multi-plane MRI-linac guidance strategy. In this work we demonstrate how interleaved acquired, orthogonal cine-MRI planes can be used for low-latency tracking of the 3D trajectory of a soft-tissue target structure.
The proposed strategy relies on acquiring a pre-treatment 3D breath-hold scan, extracting a 3D target template and performing template matching between this 3D template and pairs of orthogonal 2D cine-MRI planes intersecting the target motion path. For a 60 s free-breathing series of orthogonal cine-MRI planes, we demonstrate that the method was capable of accurately tracking the respiration related 3D motion of the left kidney.
Quantitative evaluation of the method using a dataset designed for this purpose revealed a translational error of 1.15 mm for a translation of 39.9 mm. We have demonstrated how interleaved acquired, orthogonal cine-MRI planes can be used for online tracking of soft-tissue target volumes.
Language: | English |
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Publisher: | IOP Publishing |
Year: | 2013 |
Pages: | 4943-4950 |
ISSN: | 13616560 and 00319155 |
Types: | Journal article |
DOI: | 10.1088/0031-9155/58/14/4943 |
ORCIDs: | Larsen, Rasmus |