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Conference paper

Bioprocess facility for test of Engineered CHO cell lines in Single-use bioreactors

By Decker, Marianne1,2; Lund Jensen, Kristian1,2; Javidi, Elham Maria1,2; Voldborg, Bjørn Gunnar1,2

From

Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark1

CHO Core, Translational Management, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark2

CHO project group (Scientific and CORE sections) focus is to develop new cell lines with improved homogenous glycosylation of product, titer/yield, growth profile, together with improved downstream processing. In the CORE section the findings of the CHO scientific sections are translated into an industrial relevant context by high throughput generation and screening of genetically manipulated CHO cell lines through an iterative loop.

To evaluate whether or not the genetic manipulations improved cell performance, the cell are rigorously tested within the Bioprocess facility.

Language: English
Year: 2017
Types: Conference paper
ORCIDs: Voldborg, Bjørn Gunnar

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