Journal article
Nature of bacterial colonization influences transcription of mucin genes in mice during the first week of life
In summary, our data show that development of the expression of genes encoding secreted (Muc2/Tff3) and membrane-bound (Muc1/Muc3/Muc4) mucus regulatory proteins, respectively, is distinct and that the onset of this development may be accelerated by specific groups of bacteria present or absent at the mucosal site.
| Language: | English |
|---|---|
| Publisher: | BioMed Central |
| Year: | 2012 |
| Pages: | 402 |
| ISSN: | 17560500 |
| Types: | Journal article |
| DOI: | 10.1186/1756-0500-5-402 |
| ORCIDs: | Bergström, Anders , Bahl, Martin Iain and Licht, Tine Rask |
16S rRNA <it>Escherichia coli</it> Nissle <it>Lactobacillus acidophilus</it> NCFM Animals Animals, Newborn Biology (General) Escherichia coli Escherichia coli Nissle Gene Expression Regulation, Developmental Germ free mice Germ-Free Life Intestine, Small Lactobacillus acidophilus Lactobacillus acidophilus NCFM LinRegPCR Medicine Metagenome Mice Microbial Consortia Monocolonized Muc2 protein, mouse Muc3 protein, mouse Muc4 protein, mouse Mucin-1 Mucin-2 Mucin-3 Mucin-4 Mucins Mucus Postnatal transcription onset Probiotics Q1-390 QH301-705.5 R RNA, Ribosomal, 16S Real-Time Polymerase Chain Reaction Science (General) Tff3 protein, mouse Transcription, Genetic Trefoil Factor-3 muc1 protein, mouse qPCR
