About

Log in?

DTU users get better search results including licensed content and discounts on order fees.

Anyone can log in and get personalized features such as favorites, tags and feeds.

Log in as DTU user Log in as non-DTU user No thanks

DTU Findit

Conference paper

Investigation of cleaning and regeneration methods for reliable construction of DNA cantilever biosensors

From

Department of Micro- and Nanotechnology, Technical University of Denmark1

Nanoprobes, Department of Micro- and Nanotechnology, Technical University of Denmark2

BioLabChip, Department of Micro- and Nanotechnology, Technical University of Denmark3

Bioanalytics, Department of Micro- and Nanotechnology, Technical University of Denmark4

McGill University5

Biosensing systems based on detecting changes in cantilever surface stress have attracted great interest. To achieve high reliability of measurements, high quality and high reproducibility in functionalization of the sensor surface are key points. In this paper, we investigate different methods to clean and regenerate the sensing surface of cantilever biosensors.

Perchloric acid potential sweep, potassium hydroxide-hydrogen peroxide, and piranha cleaning are investigated here. Peak-current potential differences from cyclic voltammetry, X-ray photo-electron spectroscopy and fluorescence detection are applied to characterize surface cleanliness. The experimental results show that piranha cleaning is the most reliable and efficient cleaning procedure.

Language: English
Year: 2012
Proceedings: 9th International Nanomechanical Sensing Workshop
Types: Conference paper
ORCIDs: Yi, Sun , Heiskanen, Arto , Wolff, Anders and Boisen, Anja

DTU users get better search results including licensed content and discounts on order fees.

Log in as DTU user

Access

Analysis