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Journal article

Synthesis of (+)-Coniceine via Reductive Photocyclization of Dienamides: An Entry to Indolizidines

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Department of Chemistry, Technical University of Denmark1

Université Blaise Pascal, Clermont-Ferrand II2

This paper describes the establishment of a new synthetic route to the hydrobromide salt of (+)-coniceine 1 with high enantiopurity in five steps and 8% overall yield. The key step is the reductive photocyclization of an acyclic chiral dienamide, for which a convenient one-pot synthesis is described.

Language: English
Year: 2007
Pages: 671-678
ISSN: 1362511x and 09574166
Types: Journal article
DOI: 10.1016/j.tetasy.2007.03.004
ORCIDs: Tanner, David Ackland

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