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Journal article

IEDB-AR: immune epitope database-analysis resource in 2019

From

La Jolla Institute for Allergy & Immunology1

Department of Health Technology, Technical University of Denmark2

Bioinformatics, Department of Health Technology, Technical University of Denmark3

Immunoinformatics and Machine Learning, Bioinformatics, Department of Health Technology, Technical University of Denmark4

AI for Immunological Molecules, Bioinformatics, Department of Health Technology, Technical University of Denmark5

The Immune Epitope Database Analysis Resource (IEDB-AR, http://tools.iedb.org/) is a companion website to the IEDB that provides computational tools focused on the prediction and analysis of B and T cell epitopes. All of the tools are freely available through the public website and many are also available through a REST API and/or a downloadable command-line tool.

A virtual machine image of the entire site is also freely available for non-commercial use and contains most of the tools on the public site. Here, we describe the tools and functionalities that are available in the IEDB-AR, focusing on the 10 new tools that have been added since the last report in the 2012 NAR webserver edition.

In addition, many of the tools that were already hosted on the site in 2012 have received updates to newest versions, including NetMHC, NetMHCpan, BepiPred and DiscoTope. Overall, this IEDB-AR update provides a substantial set of updated and novel features for epitope prediction and analysis.

Language: English
Publisher: Oxford University Press
Year: 2019
Pages: W502-W506
ISSN: 13624962 and 03051048
Types: Journal article
DOI: 10.1093/nar/gkz452
ORCIDs: 0000-0003-1381-7434 , 0000-0003-2136-1801 , 0000-0002-8036-2647 , Marcatili, Paolo and Nielsen, Morten

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