Conference paper
Bead Capture and Release on a Magnetic Sensor in a Microfluidic System
Planar Hall effect magnetic sensors for detection of biological agents using surface treated magnetic beads are integrated with a fluid injection system. The response of the sensors is used to evaluate bead capture rates for different bead concentrations c and fluid flow rates Q, and to monitor subsequent removal of the beads.
It is found that the capture rate scales directly with c and that it depends linearly on Q. At low Q the capture rate is only partially due to gravitational sedimentation of beads. At higher Q an additional term proportional to Q becomes important, which is attributed to capture of beads by the magnetic fields near the sensor.
It is shown that beads can be washed off the sensor surface.
| Language: | English |
|---|---|
| Year: | 2008 |
| Pages: | 242-245 |
| Proceedings: | 2008 IEEE Sensors |
| ISBN: | 1424425808 , 1424425816 , 9781424425808 and 9781424425815 |
| ISSN: | 21689229 and 19300395 |
| Types: | Conference paper |
| DOI: | 10.1109/ICSENS.2008.4716426 |
| ORCIDs: | Damsgaard, Christian Danvad and Hansen, Mikkel Fougt |
Biosensors Fluid dynamics Hall effect Hall effect transducers Magnetic sensors Microfluidics Monitoring Nanobioscience Nanotechnology Physics Sensor phenomena and characterization bead capture bead release biological agents detection flow sensors fluid injection system magnetic fields magnetic sensors microfluidic system microfluidics planar Hall effect magnetic sensors surface treated magnetic beads
