Journal article
Silver-Palladium Surfaces Inhibit Biofilm Formation
Materials and Surface Engineering, Department of Mechanical Engineering, Technical University of Denmark1
Department of Mechanical Engineering, Technical University of Denmark2
Department of Systems Biology, Technical University of Denmark3
Department of Management Engineering, Technical University of Denmark4
University of Copenhagen5
Undesired biofilm formation is a major concern in many areas. In the present study, we investigated biofilm-inhibiting properties of a silver-palladium surface that kills bacteria by generating microelectric fields and electrochemical redox processes. For evaluation of the biofilm inhibition efficacy and study of the biofilm inhibition mechanism, the silver-sensitive Escherichia coli J53 and the silver-resistant E. coli J53[pMG101] strains were used as model organisms, and batch and flow chamber setups were used as model systems.
In the case of the silver-sensitive strain, the silver-palladium surfaces killed the bacteria and prevented biofilm formation under conditions of low or high bacterial load. In the case of the silver-resistant strain, the silver-palladium surfaces killed surface-associated bacteria and prevented biofilm formation under conditions of low bacterial load, whereas under conditions of high bacterial load, biofilm formation occurred upon a layer of surface-associated dead bacteria.
Language: | English |
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Publisher: | American Society for Microbiology (ASM) |
Year: | 2009 |
Pages: | 1674-1678 |
ISSN: | 10985336 and 00992240 |
Types: | Journal article |
DOI: | 10.1128/AEM.02274-08 |
ORCIDs: | 0000-0002-9751-474X |