Journal article
Improved glucose tolerance after intensive life style intervention occurs without changes in muscle ceramide or triacylglycerol in morbidly obese subjects : Muscle lipids and life style intervention
Aim: This study investigated the effect of a 15-week life style intervention (hypocaloric diet and regular exercise) on glucose tolerance, skeletal muscle lipids and muscle metabolic adaptations in 14 female and 9 male morbidly obese subjects (age: 32.5 +/- 2.3 years, BMI: 46.1 +/- 1.9 kg m(-2)). Method: Before and after the life style intervention an oral glucose tolerance test (OGTT) was performed and a muscle biopsy was obtained in the fasted state.
Maximal oxygen uptake was measured by an indirect test. Results: After the intervention body weight was decreased (P
Language: | English |
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Year: | 2011 |
Pages: | 357-364 |
ISSN: | 17481716 and 17481708 |
Types: | Journal article |
DOI: | 10.1111/j.1748-1716.2010.02180.x |
ORCIDs: | 0000-0001-9724-5423 , 0000-0003-3117-0451 and 0000-0001-9937-5467 |