Conference paper
Reconstruction methods from hyperpolarized 13C chemical shift imaging spiral 3D data: Comparison between direct summation and gridding method
Dept of Energy and System Engineering - Univ. of Pisa, Italy1
Fond. G. Monasterio CNR - Regione Toscana - Pisa, Italy2
Inst. Clin. Phys., National Research Council - Pisa, Italy3
GE Healthcare, Broendby, Denmark4
GE Global Res., Munich, Germany5
Lab. of Med. Sci., Inst. Life Sci., Scuola Superiore Sant'Anna - Pisa, Italy6
Dept. of Inf. Eng.: EIT, Univ. of Pisa - Pisa, Italy7
Hyperpolarized 13C chemical shift imaging (CSI) is a spectroscopy technique for magnetic resonance imaging. Due to the fast decay of the hyperpolarized tracer, acquisition speed represents a key issue. Spiral trajectories are usually exploited to fast fill the K-space. Several strategies have been proposed for CSI image reconstruction form spiral trajectories, but the performances in hyperpolarized 13C CSI of these strategies have not been investigated.
In hyperpolarized 13C 3D CSI, some of the imaged metabolites may appear with very low signal, so reconstruction methods should keep SNR high to allow better viewing of metabolites' locations. In this study we compared the performances of Direct Summation (DS) and Gridding (GR) reconstruction methods.
Methods were compared evaluating SNR on reconstructed images and reconstruction time. In vivo experimental data were obtained from medium-sized animals injected with hyperpolarized 13C. DS obtained higher SNR for all metabolites of interest. On the other hand, GR was much faster. The study results may provide a useful indication on how to choose the appropriate reconstruction method for hyperpolarized 13C in vivo data acquisition.
Language: | English |
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Year: | 2012 |
Pages: | 614-617 |
Proceedings: | 2012 IEEE 9th International Symposium on Biomedical Imaging (ISBI 2012) |
ISBN: | 1457718561 , 145771857X , 145771857x , 1457718588 , 9781457718564 , 9781457718571 and 9781457718588 |
ISSN: | 19458452 and 19457928 |
Types: | Conference paper |
DOI: | 10.1109/ISBI.2012.6235623 |
CSI image reconstruction Image reconstruction Matching pursuit algorithms Reconstruction algorithms Signal to noise ratio Spirals Trajectory biomedical MRI chemical shift imaging data acquisition direct summation direct summation methods gridding method gridding reconstruction methods hyperpolarized <sup>13</sup>C chemical shift imaging spiral 3D data hyperpolarized <sup>13</sup>C in vivo data acquisition image reconstruction in vivo experimental data in vivo hyperpolarized <sup>13</sup>C metabolism magnetic resonance imaging medical image processing medium-sized animals injection non homogeneous MRI reconstruction spectroscopy technique spiral trajectories