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Interpreted as:

title:(Multi-omic AND profiling AND of AND EPO-producing AND CHO AND cell AND panel AND reveals AND metabolic AND adaptation AND to AND heterologous AND protein AND production)

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1 Conference paper

Multi-omic profiling of EPO-producing CHO cell panel reveals metabolic adaptation to heterologous protein production

Year: 2015

Language: English

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2 Conference paper

Multi-omic profiling of EPO-producing CHO cell panel reveals metabolic adaptation to heterologous protein production

discovered indications of metabolic adaptation of the amino acid catabolism in favor of heterologous protein production. We established a panel of stably EPO expressing CHO-K1 clones spanning a 25-fold productivity range and characterized the clones in batch and chemostat cultures. For this, we employed

Year: 2016

Language: English

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