Journal article
Experimental implementation and proof of principle for a radionuclidic purity test solely based on half-life measurement
In this paper we present the results of an experimental implementation of the method (Jorgensen et al., 2012) for testing the radionuclidic purity (RNP) of F-18 compounds.The overall limitations of the experimental methods and their possible impacts on RNP detectability have been identified. We have developed an GUI application for use as an easy and automated test tool in the production procedure.The test results show that this method fully complies with the requirements in the European Pharmacopoeia (Eur.
Ph.) for RNP of FDG and F-18 Sodium Fluoride. (C) 2015 Elsevier Ltd. All rights reserved.
Language: | English |
---|---|
Year: | 2016 |
Pages: | 108-115 |
ISSN: | 18729800 and 09698043 |
Types: | Journal article |
DOI: | 10.1016/j.apradiso.2015.12.038 |
ORCIDs: | Jensen, Mikael |
Computer Simulation Drug Contamination Feasibility Studies Fluorine Radioisotopes Half-Life Materials Testing Models, Chemical Pilot Projects Programming Languages Radiation Dosage Radiometry Radiopharmaceuticals Reproducibility of Results Sensitivity and Specificity User-Computer Interface