Journal article
A solid support generator of the Auger electron emitter rhodium-103m from [103Pd]palladium
Auger electron therapy is an attractive modality for targeting microscopic tumors. Rhodium-103 m (103mRh, T½ = 56.1 min) is a promising Auger electron emitter that can be obtained as the decay product of palladium-103 (103Pd, T½ = 16.99 days). 103Pd was chelated in a lipophilic derivative of the 16aneS4 macrocycle and the complex was trapped on a C18 cartridge.
Elution with dilute hydrochloric acid gave radiochemically pure 103mRh. We hypothesize this to be through a combination of the Szilard-Chalmers effect and transient ionization.
Language: | English |
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Year: | 2020 |
Pages: | 108985 |
ISSN: | 18729800 and 09698043 |
Types: | Journal article |
DOI: | 10.1016/j.apradiso.2019.108985 |
ORCIDs: | Jensen, Andreas I. , Zhuravlev, Fedor , Severin, Gregory , Magnus, Charlotte Busk , Fonslet, Jesper and Jensen, Mikael |