Journal article
Genipin cross-linked carbon dots for antimicrobial, bioimaging and bacterial discrimination
Nanjing Normal University1
Department of Health Technology, Technical University of Denmark2
Experimental & Translational Immunology, Department of Health Technology, Technical University of Denmark3
Nanomaterials and Nanobiosensors, Experimental & Translational Immunology, Department of Health Technology, Technical University of Denmark4
Multifunctional carbon dots (CDs) present enormous potential in numerous applications and have attracted widespread attention for various applications in the biomedical field. Bacterial infection is a common health issue; the development of antibacterial materials with low toxicity and good biocompatibility is becoming more important.
In this work, we synthesized a new type of nitrogen co-doped carbon dots-genipin covalent conjugate (N-CDs-GP) via hydrothermal methods. The microstructure and chemical composition of the N-CDs-GP were characterized. The biocompatibility, stability, antibacterial activity, and fluorescence performance of the N-CDs-GP were assessed.
The results revealed that N-CDs-GP possessed high biocompatibility, high light stability, and broad antibacterial activity. Additionally, selective Gram-positive bacterial imaging by N-CDs-GP provided a more rapid method of bacterial detection. The N-CDs-GP have the potential to be applied as bioimaging and antibacterial agents and for bacterial discrimination.
Language: | English |
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Year: | 2020 |
Pages: | 110930 |
ISSN: | 18734367 and 09277765 |
Types: | Journal article |
DOI: | 10.1016/j.colsurfb.2020.110930 |
ORCIDs: | 0000-0002-3776-1634 |