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Journal article · Conference paper

Investigation of the Thermostability of Bovine Submaxillary Mucin (BSM) and its Impact on Lubrication

By Madsen, Jan Busk1,2; Pakkanen, Kirsi I.1,2; Lee, Seunghwan1,2; Yang Dan

From

Department of Mechanical Engineering, Technical University of Denmark1

Materials and Surface Engineering, Department of Mechanical Engineering, Technical University of Denmark2

Bovine Submaxillary Mucin (BSM) generates thin film layers via spontaneous adsorption onto hydrophobic surfaces such as Poly(dimethylsiloxane) (PDMS) and High Density Polyethylene (HDPE). A characteristic feature of mucin is its tribological- or lubricating properties. Circular dichroismspectroscopyrevealed that BSM is thermally stable over a wide range of temperatures (5–85°C) in its conformation, and Pin-on-Disk tribometry at low speeds showed negligible influence on lubricating properties.

Employing the Mini Traction Machine, BSM was found to retain comparable lubricating properties after heating to 80°C and subsequent cooling. Random coiled secondary- and lack of tertiary structure in BSM is believed to contribute to the heat tolerance observed with regards to its conformational and lubrication properties.

Language: English
Year: 2013
Pages: 21-26
Proceedings: 3rd International Conference on Biomedical Engineering and Technology (ICBET 2013)
ISSN: 22126694 and 22126708
Types: Journal article and Conference paper
DOI: 10.1016/j.apcbee.2013.08.006
ORCIDs: Lee, Seunghwan
Keywords

Biolubrication Biotribology Bovine Submaxillary Mucin Surface Coating

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