Journal article
High frequency intergenomic recombination of suid herpesvirus 1 (SHV-1, Aujeszkys-disease virus)
Examples are given of observations made with field isolates of suid herpesvirus 1 (SHV-1) which indicate that intergenomic recombination is a common phenomenon associated with the virus. This was further confirmed by experimental co-infection of a pig with 2 virus strains with different, stable and easily identifiable genomic markers, followed by natural transmission to a group of contact pigs.
A variety of recombinants was subsequently isolated, while none of the parental strains were re-isolated from any of the pigs. It is suggested that co-invasion of cells and recombination between viral genomes play a role in the life cycle of the virus.
Language: | English |
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Publisher: | Springer-Verlag |
Year: | 1993 |
Pages: | 37-50 |
ISSN: | 14328798 and 03048608 |
Types: | Journal article |
DOI: | 10.1007/BF01309842 |
Animals Biomedicine Cells, Cultured DNA, Viral Denmark Disease Virus Herpesvirus 1, Suid Infectious Disease Infectious Diseases Life Cycle Medical Microbiology Parental Strain Polymorphism, Restriction Fragment Length Pseudorabies Recombination, Genetic Swine Swine Diseases Viral Vaccines Virology Virus Strain