Journal article
Thyroid Nodules in an 11-Year DanThyr Follow-Up Study
Context: Limited longitudinal data are available on changes in the thyroid gland structure in a population and how this is influenced by iodine fortification (IF). Objective: Our objective was to clarify how IF influenced thyroid gland structure in 2 regions with different iodine intake at baseline (Copenhagen, mild iodine deficiency [ID]; Aalborg, moderate ID).
Design and Setting: We conducted a longitudinal population-based study (DanThyr) where participants were examined before (1997) and after (2008) the Danish mandatory IF of salt (2000). Participants: We examined 2465 adults, and ultrasonography was performed by the same sonographers using the same equipment, after controlling performances.
Main Outcome Measure: Change in thyroid gland structure was evaluated. Results: The follow-up period saw an increased prevalence of multinodularity (9.8%-13.8%, P
Language: | English |
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Year: | 2014 |
Pages: | 4749-4757 |
ISSN: | 19457197 and 0021972x |
Types: | Journal article |
DOI: | 10.1210/jc.2014-2438 |