Journal article
Cytokine profile of Armenian patients with Familial Mediterranean fever
Group of Molecular and Cellular Immunology and Laboratory of Molecular Genetics, Institute of Molecular Biology, National Academy of Sciences, Yerevan, Armenia.1
Despite the well-defined genetics of FMF, limited information is available regarding the regulation of inflammation by cytokines. The levels of systemic cytokines and other markers of inflammation in FMF patients and control were measured by ELISA and Cytometric Bead Array (CBA). In FMF attack the levels of IL-6, IL-10, IL-17, TGF-beta, CRP, and sIL-2R were significantly different from the norm and FMF remission.
Inflammation in FMF involves Treg and Th17 lineages.
Language: | English |
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Year: | 2008 |
Pages: | 920-2 |
ISSN: | 18732933 and 00099120 |
Types: | Journal article |
DOI: | 10.1016/j.clinbiochem.2008.03.017 |