Journal article
Visualization of pathogenicity regions in bacteria
We show here how pathogenicity islands can be analysed using GenomeAtlases, which is a method for visualising repeats, DNA structural characteristics, and base composition of chromosomes and plasmids. We have applied this method to the E. coli plasmid pO157, and the Y. pestis plasmid pPCP1. In both cases pathogenic genes were shown to differ in A + T content and structural properties.
Furthermore, examination of an antibiotic resistance gene cluster from S. typhimurium showed that the same was true for genes encoding antibiotic resistance.
| Language: | English |
|---|---|
| Publisher: | Kluwer Academic Publishers |
| Year: | 2000 |
| Pages: | 47-51 |
| Journal subtitle: | An International Journal of Genetics and Evolution |
| ISSN: | 15736857 and 00166707 |
| Types: | Journal article |
| DOI: | 10.1023/a:1004091626474 |
Animal Genetics and Genomics Base Composition DNA, Bacterial Drug Resistance, Microbial Escherichia coli Escherichia coli O157 Genes, Bacterial Human Genetics Life Sciences Microbial Genetics and Genomics Plasmids Repetitive Sequences, Nucleic Acid Salmonella typhimurium Salmonella typhimuriumDT104 Virulence Yersenia pestis Yersinia pestis base composition pathogenicity islands
