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Journal article · Conference paper

EEG recordings as a source for the detection of IRBD

From

Technical University of Denmark1

University of Copenhagen2

Department of Electrical Engineering, Technical University of Denmark3

Biomedical Engineering, Department of Electrical Engineering, Technical University of Denmark4

The purpose of this pilot study was to develop a supportive algorithm for the detection of idiopathic Rapid Eye-Movement (REM) sleep Behaviour Disorder (iRBD) from EEG recordings. iRBD is defined as REM sleep without atonia with no current sign of neurodegenerative disease, and is one of the earliest known biomarkers of Parkinson's Disease (PD).

It is currently diagnosed by polysomnography (PSG), primarily based on EMG recordings during REM sleep. The algorithm was developed using data collected from 42 control subjects and 34 iRBD subjects. A feature was developed to represent high amplitude contents of the EEG and a semi-automatic signal reduction method was introduced.

The reduced feature set was used for a subject-based classification. With a subject specific re-scaling of the feature set and the use of an outlier detection classifier the algorithm reached an accuracy of 0.78. The result shows that EEG recordings contain valid information for a supportive algorithm for the detection of iRBD.

Further investigation could lead to promising application of EEG recordings as a supportive source for the detection of iRBD.

Language: English
Publisher: IEEE
Year: 2015
Pages: 606-609
Proceedings: 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
ISBN: 1424492696 , 1424492718 , 9781424492695 and 9781424492718
ISSN: 26940604
Types: Journal article and Conference paper
DOI: 10.1109/EMBC.2015.7318435
ORCIDs: Sørensen, Helge Bjarup Dissing

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