Journal article
Strain-Release Driven Cycloadditions for Rapid Construction of Functionalized Pyridines and Amino Alcohols
This paper describes the development of a new variant of stereoselective strain-release driven reactions (formal homo [3 + 2] dipolar cycloadditions) which utilize housane (1) to construct functionalized amino alcohols and pyridine-substituted cyclopentanes in two to three steps from simple and easily available building blocks (nitrones and pyridine N-oxides respectively).
Language: | English |
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Publisher: | American Chemical Society |
Year: | 2019 |
Pages: | 4763-4766 |
ISSN: | 15237052 and 15237060 |
Types: | Journal article |
DOI: | 10.1021/acs.orglett.9b01652 |
ORCIDs: | Tanner, David Ackland |