Journal article
Synthetic Strategies for Converting Carbohydrates into Carbocycles by the Use of Olefin Metathesis
This microreview covers recent advances in the use of ring-closing metathesis for the synthesis of carbocycles from carbohydrates. Various strategies for the synthesis of a,w-dienes from carbohydrates are presented, which give rise to a large variety of dienes with different stereochemistry, protecting groups and substituents.
Subsequent ring-closing metathesis with a ruthenium carbene complex affords highly functionalized carbocycles with ring-sizes ranging from five- to eight-membered rings. The application of these methods for the synthesis of carbocyclic natural products from carbohydrates is also demonstrated.
Language: | English |
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Year: | 2007 |
Pages: | 399-415 |
ISSN: | 10990690 and 1434193x |
Types: | Journal article |
DOI: | 10.1002/ejoc.200600614 |
ORCIDs: | Madsen, Robert |