Journal article
BYKdb: the Bacterial protein tYrosine Kinase database
Unité Bases Moléculaires et Structurales des Systèmes Infectieux; UMR 5086 CNRS - Université Claude Bernard Lyon 1; IBCP FR 3302 - 7, passage du Vercors, 69367 Lyon CEDEX 07, France and1
Bacterial tyrosine-kinases share no resemblance with their eukaryotic counterparts and they have been unified in a new protein family named BY-kinases. These enzymes have been shown to control several biological functions in the bacterial cells. In recent years biochemical studies, sequence analyses and structure resolutions allowed the deciphering of a common signature.
However, BY-kinase sequence annotations in primary databases remain incomplete. This prompted us to develop a specialized database of computer-annotated BY-kinase sequences: the Bacterial protein tyrosine-kinase database (BYKdb). BY-kinase sequences are first identified, thanks to a workflow developed in a previous work.
A second workflow annotates the UniProtKB entries in order to provide the BYKdb entries. The database can be accessed through a web interface that allows static and dynamic queries and offers integrated sequence analysis tools. BYKdb can be found at http://bykdb.ibcp.fr.
Language: | Undetermined |
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Publisher: | Oxford University Press |
Year: | 2012 |
Pages: | D321-D324 |
ISSN: | 13624962 and 03051048 |
Types: | Journal article |
DOI: | 10.1093/nar/gkr915 |