Conference paper
Bioimpedance measurements on human neural stem cells as a benchmark for the development of smart mobile biomedical applications
University of Oslo1
Center for Intelligent Drug Delivery and Sensing Using Microcontainers and Nanomechanics, Department of Health Technology, Technical University of Denmark2
Department of Biotechnology and Biomedicine, Technical University of Denmark3
Biomaterial Microsystems, Nanofabrication, National Centre for Nano Fabrication and Characterization, Technical University of Denmark4
Biomaterial Microsystems, Department of Micro- and Nanotechnology, Technical University of Denmark5
Department of Micro- and Nanotechnology, Technical University of Denmark6
Drug Delivery and Sensing, Department of Health Technology, Technical University of Denmark7
Nanofabrication, National Centre for Nano Fabrication and Characterization, Technical University of Denmark8
National Centre for Nano Fabrication and Characterization, Technical University of Denmark9
Universidad Autónoma de Madrid10
...and 0 moreOver the past 30 years, stem cell technologies matured from an attractive option to investigate neurodegenerative diseases to a possible paradigm shift in their treatment through the development of cell-based regenerative medicine (CRM). Implantable cell replacement therapies promise to completely restore function of neural structures possibly changing how we currently perceive the onset of these conditions.
One of the major clinical hurdles facing the routine implementation of stem cell therapy is the limited and inconsistent benefit observed thus far. While unclear, numerous pre-clinical and a handful of clinical cell fate imaging studies point to poor cell retention and survival. Coupling the need to better understand these mechanisms while providing scalable approaches to monitor these treatments in both pre-clinical and clinical scenarios, we show a proof of concept bioimpedance electronic platform for the Agile development of smart and mobile biomedical applications like neural implants or highly portable monitoring devices.
Language: | English |
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Year: | 2019 |
Proceedings: | XVII International Conference on Electrical Bioimpedance |
Types: | Conference paper |
DOI: | 10.29007/4b1g |
ORCIDs: | Heiskanen, Arto , Keller, Stephan Sylvest and Emnéus, Jenny |