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Conference paper

Real-time optical monitoring of cell culture in centrifugal microfluidics

In Microtas 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences — 2020, pp. 1039-1040
From

Nanoprobes, Drug Delivery and Sensing, Department of Health Technology, Technical University of Denmark1

Drug Delivery and Sensing, Department of Health Technology, Technical University of Denmark2

Department of Health Technology, Technical University of Denmark3

Center for Intelligent Drug Delivery and Sensing Using Microcontainers and Nanomechanics, Department of Health Technology, Technical University of Denmark4

University of Copenhagen5

University of Hyogo6

We present a cellular-resolution (2 Pm) optical microscope that is rotating with a disc-shaped centrifugal microfluidics cell culture platform, inside an incubator. The microscope is powered wirelessly and is composed of a homemade optics and a wireless spy camera. The human cervical cancer cell line was, seeded and cultured on the disc, where their attachment and growth was monitored with the microscope.

The microscope can wirelessly transmit microscopic images through the incubator to an external PC, which enables real-time (30 frames per second), continuous (without time limit) and remote (live Internet streaming) monitoring of the cell-based assays.

Language: English
Publisher: Chemical and Biological Microsystems Society
Year: 2020
Pages: 1039-1040
Proceedings: 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
ISBN: 1733419012 and 9781733419017
Types: Conference paper
ORCIDs: Hwu, Edwin En Te , Thoppe Rajendran, Sriram , Zor, Kinga and Boisen, Anja

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