Journal article
Photonic crystal fiber based evanescent-wave sensor for detection of biomolecules in aqueous solutions
Glass Components and Materials, Department of Photonics Engineering, Technical University of Denmark1
Department of Photonics Engineering, Technical University of Denmark2
Bioneer A/S3
Crystal Fibre A/S4
Fiber Optics, Devices and Non-linear Effects, Department of Photonics Engineering, Technical University of Denmark5
We demonstrate highly efficient evanescent-wave detection of fluorophore-labeled biomolecules in aqueous solutions positioned in the air holes of the microstructured part of a photonic crystal fiber. The air-suspended silica structures located between three neighboring air holes in the cladding crystal guide light with a large fraction of the optical field penetrating into the sample even at wavelengths in the visible range.
An effective interaction length of several centimeters is obtained when a sample volume of less than 1 µL is used.
Language: | English |
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Year: | 2004 |
Pages: | 1974-1976 |
ISSN: | 10944087 , 15394794 and 01469592 |
Types: | Journal article |
DOI: | 10.1364/OL.29.001974 |