Conference paper
Streamline tractography for 3D mapping of axon bundle organization in one MRI voxel using ultra-high resolution synchrotron radiation imaging
Department of Applied Mathematics and Computer Science, Technical University of Denmark1
Visual Computing, Department of Applied Mathematics and Computer Science, Technical University of Denmark2
University of Copenhagen3
University of Southern Denmark4
The European Synchrotron5
Statistics and Data Analysis, Department of Applied Mathematics and Computer Science, Technical University of Denmark6
We present an efficient image analysis pipeline that enables us to reveal white matter organization in high-resolution 3D non-MRI structural datasets, in cases where a strict image segmentation is not required nor possible. We apply the method to a synchrotron X-ray holographic tomography scan from a healthy mouse sample, and show the organization of axon bundles in a region covering parts of the corpus callosum and the cingulum.
The method has a potential to improve our general understanding of white matter organization and our ability to generate realistic phantoms for validation of microstructure modelling from low-resolution diffusion MRI scans.
| Language: | English |
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| Publisher: | The International Society for Magnetic Resonance in Medicine |
| Year: | 2020 |
| Pages: | 1-3 |
| Proceedings: | 2020 ISMRM & SMRT Virtual Conference & Exhibition |
| Types: | Conference paper |
| ORCIDs: | Kjer, Hans Martin , Andersson, Mariam , Dahl, Anders Bjorholm , Dahl, Vedrana Andersen and Dyrby, Tim Bjørn |
