Journal article
Biomedical Applications of MXene-Integrated Composites: Regenerative Medicine, Infection Therapy, Cancer Treatment, and Biosensing
Zanjan University of Medical Sciences1
Italian Institute of Technology2
Shanghai University3
Damghan University4
Institute for Advanced Studies in Basic Sciences, Zanjan5
Hamedan University of Medical Sciences and Health Services6
University of Groningen7
Manufacturing Engineering, Department of Civil and Mechanical Engineering, Technical University of Denmark8
Department of Civil and Mechanical Engineering, Technical University of Denmark9
Islamic Azad University10
University of Bradford11
...and 1 moreMXenes (viz., transition metal carbides, carbonitrides, and nitrides) have emerged as a new subclass of 2D materials. Due to their outstanding physicochemical and biological properties, MXenes have gained much attention in the biomedical field in recent years, including drug delivery systems, regenerative medicine, and biosensing.
Additionally, the incorporation of MXenes into hydrogels has garnered significant interest in biomedical engineering as an electroactive and mechanical nanoreinforcer capable of converting nonconductive scaffolds into excellent conductors of electricity with an impressive effect on mechanical properties for the engineering of electroactive organs and tissues such as cardiac, skeletal muscle, and nerve.
However, many questions and problems remain unresolved that need to be answered to usher these 2D materials toward their true destiny. Thus, this review paper aims to provide an overview of the design and applications of MXene-integrated composites for biomedical applications, including cardiac tissue engineering, wound healing, infection therapy, cancer therapy, and biosensors.
Moreover, the current challenges and limitations of utilizing MXenes in vivo are highlighted and discussed, followed by its prospects as a guideline toward possible various futuristic biomedical applications. This review article will inspire researchers, who search for properties, opportunities, and challenges of using this 2D nanomaterial in biomedical applications.
Language: | English |
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Year: | 2022 |
Pages: | 2203430 |
ISSN: | 16163028 and 1616301x |
Types: | Journal article |
DOI: | 10.1002/adfm.202203430 |
ORCIDs: | 0000-0003-2456-0961 , 0000-0002-8206-3325 and Mehrali, Mehdi |
2D materials Biological properties Biomedical applications Integrated composites MXenes SDG 3 - Good Health and Well-being
biological properties biomedical applications integrated composites