Preprint article · Journal article
Enantioselective γ-Lactam Synthesis via Palladium-Catalyzed Intramolecular Asymmetric Allylic Alkylation
A Pd(0)-catalyzed intramolecular allylic alkylation in the presence of (R)-3,5-T-Bu-MeOBIPHEP takes place in up to 92:8 er in agreement with DFT calculations and provides easy access to enantioenriched disubstituted γ-lactams.
Language: | English |
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Publisher: | Georg Thieme Verlag |
Year: | 2009 |
Pages: | 1441-1444 |
ISSN: | 14372096 and 09365214 |
Types: | Preprint article and Journal article |
DOI: | 10.1055/s-0029-1216747 |