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Preprint article · Journal article

Enantioselective γ-Lactam Synthesis via Palladium-Catalyzed Intramolecular Asymmetric Allylic Alkylation

In Synlett 2009, Volume 2009, Issue 09, pp. 1441-1444

A Pd(0)-catalyzed intramolecular allylic alkylation in the presence of (R)-3,5-T-Bu-MeOBIPHEP takes place in up to 92:8 er in agreement with DFT calculations and provides easy access to enantioenriched disubstituted γ-lactams.

Language: English
Publisher: Georg Thieme Verlag
Year: 2009
Pages: 1441-1444
ISSN: 14372096 and 09365214
Types: Preprint article and Journal article
DOI: 10.1055/s-0029-1216747

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