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title:(Heterologous AND protein AND production AND in AND Streptomyces AND lividans)

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1 PhD Thesis

Heterologous protein production in Streptomyces lividans

Rattleff, Stig

Technical University of Denmark — 2013

Alternative hosts for expressing heterologous proteins have recently gained an increased attention. Actinomycetes, and among these especially the Streptomycetes are considered promising candidates, since they through their saprophytic lifestyle are capable of excreting large amounts of proteins

Year: 2013

Language: English

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2 Conference paper · Journal article

Establishing a high throughput method for medium optimization – a case study using Streptomyces lividans as host for production of heterologous protein

Actinomycetes are widely known for production of antibiotics, though as hosts for heterologous protein expression they show great potential which should be further developed. Streptomyces lividans is especially interesting due to very low endogenous protease activity and the capability to secrete

Year: 2012

Language: English

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